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Methedrone (para-methoxymethcathinone, 4-methoxymethcathinone, bk-PMMA, PMMC, methoxyphedrine, 4-MeOMC) is a recreational drug of the cathinone chemical class. Chemically, methedrone is closely related to para-methoxymethamphetamine (PMMA), methylone and mephedrone. Methedrone received media attention in 2009 after the death of two young Swedish men. In both cases toxicology analysis showed methedrone was the only drug present in both men during the time of their overdose and subsequent deaths
Methedrone is a synthetic cathinone. It is related to the parent compound cathinone. Methedrone belongs to the phenethylamine family due to the presence of the cyclic group of atoms C6H5 in which six carbons bind to form a hexagonal ring with five hydrogens each bonding to a carbon and the remaining carbon bonded to an atom or group of atoms other than hydrogen.
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There is no articles about the reactivity of methedrone.
Figure 1: Synthesis of methedrone
The synthesis of methedrone describe in figure passage. and can be written as the following steps.
Bromination of 1-(4-methoxyphenyl)propan-1-one to 2-bromo-1-(4-methoxyphenyl)propan-1-one.
A reaction with methylamine in which the 2-bromo-1-(4-methoxyphenyl)propan-1-one becomes 1-(4-methoxyphenyl)-2-(methylamino)propan-1-ol.
The final step is a reaction with potassium permanganate.
The synthesis of mephedrone, a structurally similar compound with only one less ether group than methedrone,
Methedrone can be purchased legally in Europe (excluding Sweden) and in most states in the US on the Internet, but also it can also be found at head shops and other retailers. It is, along with other new or unregulated synthetic drugs and research chemicals, commonly labele as a “bath salt”
In conclusion, Methedrone is a research chemical and its euphoric and stimulant properties can be abused.
Meanwhile, Similarly to MDMA it can be administere through insufflation, ingestion, smoking, rectal, and intravenous routes; however, it differ greatly in both duration and toxicity and great care is take when using due to the lack of medical literature available common among designer drugs